Systematic reviews on the treatment of IH
| Systematic review | Studies included. Therapy | Patients (n) | Age at treatment initiation | Dose | Duration of therapy | Any improvement | Adverse events |
|---|---|---|---|---|---|---|---|
| Marqueling et al56 | N=41 2008–2012 Propranolol | 1264 | 6.6 m (3d to 10 y) | Mean: 2.1 mg/kg/d | Mean 6.4 m Range 1 wk to 15 m | 98% Range 82–100% | See text |
| Izadpanah et al57 | N total=41 N Propr=25 N Cortic. 16 | 795 2629 | 12±6 m Not reported | 2 mg/kg/d 3SD 2–3 mg/kg/d | 4 wk −12 m 4–8 wk | 97.3% 71% p<0.0001 | See text |
Cortic, corticosteroids; d, day; IH, infantile haemangioma; m, months; propr., propranolol; wk, weeks; y, years.