Comparison of neonatal hypoxemic respiratory failure (NRF) from three studies of 12 consecutive months each
| Variables | Nationwide | Hebei | Nationwide |
|---|---|---|---|
| Year | 2004–2005 | 2006–2007 | 2008–2009 |
| Province*, n | 14 | 1 | 24 |
| NICU, n | 23 | 14 | 55 |
| NICU admissions, n | 13 070 | 11 100 | 34 842 |
| Admissions/NICU, n/n | 568 | 793 | 633 |
| NRF, n | 1722 | 1875 | 6864 |
| Incidence of NRF, % | 13.2 | 16.9 | 19.7 |
| NRF/NICU, n/n | 75 | 134 | 125 |
| GA, weeks, mean±SD | 35.2±4 | 35.0±4 | 34.9±3.9 |
| BW, g, mean±SD | 2316±831 | 2267±804 | 2314±819 |
| Male, % | 75.5 | 72.3 | 70.9 |
| Survival, % | 67.9 | 68.6 | 75.3 |
| CPAP, n (%) | 905 (52.6) | 908 (69.4) | 4691 (69.2) |
| CMV, n (%) | 1007 (58.5) | 875 (46.7) | 3925 (57.9) |
| HFOV, n (%) | 47 (2.7) | 346 (5.1) | |
| RDS, n (% of NRF) | 602 (35) | 881 (47) | 3013 (44) |
| Antenatal steroids†, % | 31.7 | 32.1 | 25.1 |
| Survival, % | 66.2 | 67.3 | 76.3 |
| Surfactant use, % | 36 | 58.3 | 54.7 |
| Survival, % | 78.8 | 73.7 | 79.9 |
| Non-surfactant, % | 64 | 41.7 | 45.3 |
| Survival, % | 63.5 | 58.6 | 72.0 |
| <1500 g, n (%) | 331 (17.7) | 861 (12.5) | |
| Survival, % | 45.3 | 43.9 | |
| <1000 g, n (%) | 45 (2.6)‡ | 38 (2.0) | 124 (1.8) |
| Survival, % | 37.8 | 26.3 | 27.4 |
| MAS, n (% of NRF) | 163 (9.5) | 146 (7.8) | 480 (7.0) |
| Survival, % | 60.7 | 66.9 | 70.3 |
| Pneumonia/sepsis, n (% of NRF) | 316 (18.4) | 469 (25.1) | 1489 (21.7) |
| Survival, % | 74 | 68 | 71.4 |
| Cost of stay§, Yuan (103) | 10.5 | 10 (1, 19) | 11.8 (6.6, 19.7) |
| Reference | 8 24 | 11 | 25 |
*Province refers to provinces, autonomous regions and special metropolis areas.
†Data from those with GA below 35 weeks.
‡From those below 28 weeks.
§Cost of hospital stay for NRF survivors, median (IQR).
BW, birth weight; CMV, conventional ventilation; CPAP, continuous positive airway pressure; GA, gestational age; HFOV, high frequency oscillatory ventilation; MAS, meconium aspiration syndrome; NICU, neonatal intensive care unit; RDS, respiratory distress syndrome.