Classification of outcome in PROGRAMS at 2 years of age corrected for prematurity
| GM-CSF – control | ||||||
|---|---|---|---|---|---|---|
| Outcome | GM-CSF (n=139) | Control (n=141) | RR | 95% CI | ||
| Death | 33/134 | 24% | 31/141 | 22% | 1.1 | 0.7 to 1.7 |
| Survival without severe disability‡ | 87/134 | 65% | 87/131 | 66% | 1.0 | 0.8 to 1.2 |
| Survival without disability‡ | 63/134 | 47% | 68/131 | 52% | 0.9 | 0.7 to 1.2 |
| Overall function in survivors† | ||||||
| Severe disability‡ | 14/101 | 14% | 13/100 | 13% | 1.2§ | 0.5 to 2.7 |
| Other disability | 24/101 | 24% | 19/100 | 19% | 1.4§ | 0.7 to 2.7 |
| No disability | 63/101 | 62% | 68/100 | 68% | – | – |
| Neurological abnormality | 7/101 | 7% | 9/100 | 9% | 0.8 | 0.3 to 2.0 |
* Unable to trace or abroad.
↵† One not done, two assessed by non-study paediatrician but insufficient information to classify disability.
↵‡ Using criteria outlined in references 11 and 12. Malformation and growth domains have been excluded from the disability criteria.
↵§ RR ratio estimated by multinomial logistic regression.
GM-CSF, granulocyte-macrophage colony-stimulating factor.