Case summaries of neonates and chitotriosidase activity on diagnosis of the fungal infection
| Neonate | BW (g) | EGA (week) | Fungal species | Neonatal problems | Chitotriosidase | |
|---|---|---|---|---|---|---|
| Plasma(nmol/ml/h) | Urine (nmol/mg creatine/h) | |||||
| BPD, bronchopulmonary dysplasia; BW, birth weight; DIC, disseminated intravascular coagulation; EGA, estimated gestational age; IPPV, intermediate positive pressure ventilation; IVH, intraventricular haemorrhage; NEC, necrotising enterocolitis; PDA, patent ductus arteriosus; RDS, respiratory distress syndrome. | ||||||
| I | 950 | 27 | C albicans | RDS, apnea, IPPV, PDA,septic shock | 59 | 312 |
| II | 720 | 25 | C albicans | RDS, IPPV, IVH, PDA,BPD, NEC, DIC, ascites,septic shock | 432 | 10 060 |
| III | 830 | 25 | A niger | Asphyxia, RDS, IPPV,pneumonothorax, septic shock | 32 | 210 |
| IV | 900 | 28 | C albicans | RDS, IPPV, PDA, septic shock | 123 | 3275 |
| V | 1000 | 29 | C albicans | RDS, IPPV, PDA | 46 | 661 |
| VI | 3620 | Term | C albicans | Lethargy, seizures,meningitis, CT scan (+),EEG (−) | 40 | 83 |
| VII | 3870 | Term | C albicans | Renal failure,osteomyelitis | 95 | 560 |
| VIII | 1750 | Term | C albicans | Meconium staining,hypoglycaemia, abscess | 0.0 | 0.0 |
| Normal (n = 10) | – | – | – | – | 0–48 | 0–70 |