Table 1

 Significant univariate associations with cerebral palsy, severe motor disability, and developmental index scores

VariableCerebral palsySevere motor disabilityPDIMDI
OR95% CIOR95% CICoeff95% CICoeff95% CI
†Parenchymal pathology and/or ventriculomegaly on final cranial ultrasound scan.
*p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.
OR, Odds ratio; Coeff, regression coefficient which is equivalent to the effect size in development index units; ROP, retinopathy of prematurity.
Afro-Caribbean0.950.39 to 2.280.750.22 to 2.62−0.05−4.45 to 4.35−9.63−13.95 to −5.30***
Maternal education ⩾A level0.570.26 to 1.240.540.18 to 1.652.18−1.31 to 5.663.830.32 to 7.35*
Primigravida0.820.42 to 1.581.050.45 to 2.422.75−0.39 to 5.891.24−1.99 to 4.48
>2 previous perinatal deaths0.560.26 to 1.210.490.16 to 1.45−0.6−4.04 to 2.84−4.34−7.82 to −0.87*
Maternal smoking in pregnancy1.510.81 to 2.811.100.47 to 2.57−3.96−7.15 to −0.77*−1.72−5.04 to 1.61
Male2.401.30 to 4.45***2.140.95 to 4.82−4.16−7.13 to −1.18**−3.08−6.18 to 0.02
Antepartum steroids0.740.60 to 1.490.40.17 to 0.92*2.23−1.50 to 5.973.44−0.37 to 7.25
Chorioamnionitis0.350.14 to 0.85*0.510.18 to 1.53−1.17−4.57 to 2.23−1.91−5.46 to 1.64
Prolonged rupture of membranes1.060.55 to 2.071.100.46 to 2.63−0.08−3.38 to 3.22−1.80−5.20 to 1.60
Vaginal breech delivery2.271.21 to 4.26*2.481.11 to 5.53*3.780.15 to 7.40*2.67−1.16 to 6.50
Moved hospitals within 24 h4.492.09 to 9.65****6.822.84 to 16.38****−1.25−6.54 to 4.050.86−4.92 to 6.65
Pulmonary haemorrhage2.651.05 to 6.70*6.692.51 to 17.84****−2.19−8.43 to 4.05−1.73−8.12 to 4.65
Enteral feeds by 7 days0.270.14 to 0.52***0.290.12 to 0.72**0.94−2.09 to 3.961.94−1.22 to 5.10
Breast milk in hospital0.490.23 to 1.040.360.14 to 0.88*5.751.36 to 10.14*1.89−2.63 to 6.42
Supplemental oxygen at 36 weeks2.291.03 to 5.12*3.170.93 to 10.83−5.07−8.32 to −1.81**−5.12−8.46 to −1.78**
>6 weeks systemic steroids2.261.02 to 4.98*4.301.76 to 10.52**−3.9−8.70 to 0.90−2.54−7.99 to 2.91
>8 weeks systemic steroids4.741.69 to 13.28**4.761.52 to 14.90**−3.71−11.24 to 3.83−8.21−17.06 to 0.64
Treatment for ROP1.150.51 to 2.572.461.00 to 6.01*−4.58−8.62 to −0.53*−1.05−5.47 to 3.36
Significantly abnormal USS†5.172.60 to 10.27****6.943.03 to 15.88****−6.5−11.45 to −1.54**−0.21−5.28 to 4.87