Continuous clinical variables adjusted for gestational age and clinical risk index for babies (CRIB) score
| Outcome | Median (Q1–Q3)* | Adjusted HR | p Value | |
|---|---|---|---|---|
| HR | 95% CI | |||
| Analysis was performed using Cox proportional hazards regression. Adjusted HRs were obtained in a multivariate regression model. In all regression models, data for infants who died (n = 24, table 3) or were transferred (group 1, 2, 3: n = 3, 1, 3 respectively) were censored. No significant effects of sex and intrauterine were found in addition to gestational age at delivery and CRIB score. | ||||
| *Q1 and Q3 list the number of days that 25th and 75th centiles of infants remained on ventilation, oxygen, or stayed in the hospital. | ||||
| PDA, Patent ductus arteriosus; HR, hazard ratio. | ||||
| Duration of ventilation | 25 (7–53) | |||
| PDA insignificant | 14 (4–31) | 1.00 | ||
| PDA closed | 37 (20–62) | 0.86 | 0.63 to 1.19 | 0.336 |
| PDA open | 60 (41–75) | 0.70 | 0.44 to 1.11 | 0.130 |
| Duration of oxygen | 62 (20–103) | |||
| PDA insignificant | 48 (20–103) | 1.00 | ||
| PDA closed | 90 (76–103) | 0.89 | 0.63 to 1.27 | 0.526 |
| PDA open | 85 (44–120) | 1.20 | 0.73 to 1.98 | 0.476 |
| Hospital stay | 91 (71–119) | |||
| PDA insignificant | 80 (65–100) | 1.00 | ||
| PDA closed | 111 (8–127) | 0.75 | 0.53 to 1.07 | 0.177 |
| PDA open | 111 (94–159) | 0.85 | 0.48 to 1.50 | 0.579 |