Comparison of sensitivity, specificity, and positive and negative predictive values of different centile cut off values for serum cortisol concentration (nmol/l; indicated in parentheses) for diagnosis of early hypotension in very low birthweight infants
| 25th centile | 50th centile | 75th centile | 90th centile | |||||
|---|---|---|---|---|---|---|---|---|
| 0 min (⩽115) | 30 min (⩽261) | 0 min (⩽198) | 30 min (⩽384) | 0 min (⩽343) | 30 min (⩽564) | 0 min (⩽560) | 30 min (⩽797) | |
| PPV, positive predictive value; NPV, negative predictive value. | ||||||||
| Sensitivity | 0.23 | 0.27 | 0.47 | 0.29 | 0.77 | 0.76 | 0.92 | 0.96 |
| Specificity | 0.91 | 0.93 | 0.80 | 0.93 | 0.43 | 0.50 | 0.27 | 0.23 |
| PPV | 0.82 | 0.88 | 0.81 | 0.89 | 0.71 | 0.73 | 0.70 | 0.69 |
| NPV | 0.40 | 0.41 | 0.46 | 0.42 | 0.51 | 0.54 | 0.67 | 0.77 |