Characteristic | Group A (n = 50) | Group B (n = 38) | p Value |
---|---|---|---|
Study population divided into two groups according to serum IL6 level at 12 hours of postnatal age: A, ⩽ 100 pg/ml; B, > 100 pg/ml. | |||
*Values are given as median and range. | |||
IL, interleukin; CRIB, clinical risk index for babies; PDA, patent ductus arteriosus. | |||
Gestational age (weeks) | 26+0 (23+2−27+6)* | 25+1 (23+2−27+2)* | 0.09 |
Birth weight (g) | 652 (333–1000)* | 705 (470–910)* | 0.18 |
Male/female | 25/25 | 18/20 | 1.0 |
Antenatal steroids | 47(94%) | 35(92%) | 0.43 |
Cord blood pH | 7.32 (6.9–7.46)* | 7.32 (7.13–7.44)* | 0.62 |
CRIB score | 8(1–21) | 8(1–20) | 0.063 |
Catecholamine treatment | 31(62%) | 35(92%) | 0.002 |
C reactive protein > 5 mg/l | 7(14%) | 15(39%) | 0.012 |
IL6 concentration (pg/ml) | 12(0–96)* | 1000 (114–50 000)* | 0.0001 |
PDA | 34(68%) | 32(84%) | 0.22 |
Mechanical ventilation | 48(96%) | 38(100%) | 0.25 |