Basic and clinical data of 62 newborn infants receiving 66 courses of enoxaparin
| No of courses of enoxaparin | |||||
|---|---|---|---|---|---|
| Predictor | One | Two | Gestational age (weeks) | Birth weight (g) | Length of treatment (days) |
| Data are reported as mean (SD). n represents number of children. Four children received more than one course of enoxaparin. | |||||
| AV, Assisted ventilation; CHD, congenital heart disease; NICU, neonatal intensive care unit; INR, international normalised ratio. | |||||
| Anti-(factor Xa) range | |||||
| 0.1–0.3 (n=8) | 8 | 38.5 (2.7) | 3200 (1299) | 21.1 (16.6) | |
| 0.5–1.0 (n=54) | 50 | 4 | 37.9 (3.2) | 3072 (943) | 29.7 (18.6) |
| Gestational age (weeks) | |||||
| <37 (n=15) | 15 | 33.5 (2.7) | 1889 (808) | 30.5 (21.8) | |
| ⩾37 (n=47) | 43 | 4 | 39.5 (1.3) | 3478 (661) | 27.9 (17.4) |
| AV + NICU (n=24) | 22 | 2 | 37.4 (3.4) | 2878 (914) | 31.3 (19.3) |
| NICU (n=17) | 15 | 2 | 37.9 (3.7) | 3362 (1212) | 22.9 (17.2) |
| Standard care (n=21) | 21 | 38.9 (2.3) | 3094 (814) | 30.0 (18.3) | |
| CHD (n=48) | 44 | 4 | 38.7 (2.3) | 3213 (791) | 29.3 (17.6) |
| Non-CHD (n=14) | 14 | 35.6 (4.4) | 2664 (1397) | 26.1 (21.6) | |
| Impaired renal/liver function | |||||
| Yes (n=12) | 12 | 2 | 37.8 (2.7) | 3132 (1014) | 29.5 (20.8) |
| No (n=48) | 46 | 2 | 38.1 (3.3) | 3074 (978) | 28.3 (17.9) |
| Thrombocytopenia | |||||
| <120×109/l (n=40) | 38 | 2 | 38.4 (3.0) | 3133 (949) | 29.5 (19.0) |
| ⩾120×109/l (n=19) | 17 | 2 | 37.3 (3.4) | 2970 (1081) | 28.4 (18.4) |
| Abnormal INR | |||||
| >1.5 (n=9) | 6 | 3 | 37.9 (2.1) | 2907 (688) | 27.6 (14.9) |
| ⩽1.5 (n=50) | 49 | 1 | 38.1 (3.3) | 3133 (1044) | 29.4 (19.0) |