Baseline (n=35) | 3 h (n=35) | 24 h (n=35) | 30 h (n=34) | 48 h (n=31) | ||||||
---|---|---|---|---|---|---|---|---|---|---|
NT | HT | NT | HT | NT | HT | NT | HT | NT | HT | |
Values are mean (SD). | ||||||||||
*Tricuspid regurgitation velocity evaluated in 27 animals. | ||||||||||
MV, Mitral valve velocity; TV, tricuspid valve velocity; PV, pulmonary valve velocity; AV, aortic valve velocity; CO, cardiac output; TR, tricuspid regurgitation velocity; HR, heart rate; MABP, mean arterial blood pressure. | ||||||||||
Aorta diameter (mm) | 5.9 (0.23) | 5.6 (0.6) | 5.9 (0.24) | 5.7 (0.61) | 6.0 (0.24) | 5.6 (0.59) | 6.0 (0.23) | 5.6 (0.59) | 6.0 (0.24) | 5.7 (0.6) |
MV (m/s) | 0.76 (0.14) | 0.76 (0.17) | 0.86 (0.12) | 0.92 (0.19) | 0.79 (0.12) | 0.75 (0.11) | 0.74 (0.11) | 0.74 (0.12) | 0.74 (0.16) | 0.69 (0.08) |
TV (m/s) | 0.62 (0.08) | 0.62 (0.11) | 0.71 (0.14) | 0.75 (0.11) | 0.60 (0.15) | 0.63 (0.12) | 0.54 (0.09) | 0.58 (0.10) | 0.55 (0.10) | 0.56 (0.11) |
PV (m/s) | 0.96 (0.19) | 0.97 (0.18) | 1.04 (0.14) | 0.98 (0.13) | 0.91 (0.17) | 0.92 (0.18) | 0.89 (0.15) | 0.99 (0.21) | 0.89 (0.17) | 0.95 (0.20) |
AV (m/s) | 1.2 (0.17) | 1.1 (0.21) | 1.2 (0.17) | 1.0 (0.14) | 1.2 (0.19) | 1.0 (0.19) | 1.2 (0.17) | 1.2 (0.17) | 1.2 (0.22) | 1.2 (0.15) |
Stroke volume (ml) | 1.97 (0.37) | 1.82 (0.35) | 2.06 (0.51) | 2.11 (0.41) | 1.89 (0.41) | 1.85 (0.34) | 1.88 (0.39) | 1.98 (0.35) | 1.80 (0.31) | 2.03 (0.38) |
CO (litres/kg/min) | 0.38 (0.06) | 0.37 (0.09) | 0.41 (0.08) | 0.43 (0.09) | 0.34 (0.08) | 0.30 (0.08) | 0.35 (0.08) | 0.33 (0.06) | 0.32 (0.09) | 0.30 (0.08) |
TR* (m/s) | 3.1 (0.34) | 3.0 (0.49) | 3.4 (0.42) | 3.0 (0.45) | 3.0 (0.27) | 3.0 (0.42) | 3.0 (0.31) | 3.1 (0.38) | 2.9 (0.35) | 2.9 (0.23) |
HR (beats/min) | 194 (18) | 184 (29) | 202 (32) | 197 (23) | 187 (35) | 166 (35) | 172 (36) | 173 (30) | 169 (35) | 163 (30) |
MABP (mm Hg) | 61 (9.9) | 55 (7.4) | 75 (11.0) | 80 (15.1) | 66 (13.7) | 67 (11.9) | 68 (12.4) | 63 (15.5) | 66 (11.5) | 72 (15.5) |