Second cohort: clinical characteristics of infants and von Willebrand factor (vWF) function
| Preterm | ||||
|---|---|---|---|---|
| Characteristics | Healthy (n=38) | HMD (n=26) | Full term (n=23) | Adult (n=24) |
| All values are mean (SD). | ||||
| Adult values significantly lower than all infant values for each characteristic, p<0.01. | ||||
| *p<0.01 compared with full term. | ||||
| Gestational age (weeks) | 32.2 (3.0) | 28.5 (2.7) | 39.1 (1.3) | – |
| Birth weight (g) | 1613.1 (693.3)* | 1192.3 (479.9)* | 3250.4 (530.7) | – |
| vWF antigen (%) | 165.1 (27.4) | 162.8 (39.7) | 166.5 (33.5) | 93.4 (22.6) |
| (n=20) | (n=23) | (n=17) | (n=24) | |
| vWF collagen binding (arbitrary units) | 0.89 (0.26) | 0.77 (0.30) | 1.11 (0.12) | 0.55 (0.09) |
| (n=25) | (n=10) | (n=6) | (n=24) | |
| Ristocetin cofactor (%) | 193.8 (73.3) | 228.6 (74.7) | 253.3 (88.2) | 89.6 (16.8) |
| (n=20) | (n=23) | (n=17) | (n=24) | |