Summary of clinical data for nine children treated for vein of Galen aneurysmal malformations (VGAMs) presenting with cardiac failure in neonatal period
| Patient | Antenatal diagnosis | Age at admission (hours) | Age at intubation (hours) | Lactate/base excess after stabilisation (mmol/l) | Lasjaunias score* | Initial neuroimaging size (AP × transverse × craniocaudal) |
|---|---|---|---|---|---|---|
| *Neonatal rating score proposed by Lasjaunias and ter Brugge10 derived from measures of cardiac, cerebral, hepatic, renal, and respiratory function. A total score of less than 8 results in a decision not to treat; a score of 8–12 prompts emergency endovascular intervention; a score greater than 12 recommends medical treatment alone and delayed embolisation at 5 months of age. | ||||||
| BE, Base excess. | ||||||
| 1 | No | 8 | 6 | 2.5/BE 10 | 6 | Brain parenchyma normal (MRI); size of lesion 2.9×3.9×2.7cm |
| 2 | Yes (31 weeks) | 2 | 1 | 3.5/BE −5 | 10 | Brain parenchyma normal (MRI); size of lesion 1.5×1.8×1.9cm |
| 3 | No | 2 | 5 min | 9.3/BE −12.9 | 3 | Brain parenchyma abnormal (US); size of lesion 4.4×2.3×2.5 cm |
| 4 | No | 36 | 33 | 10.9/BE −8.4 | 6 | Brain parenchyma abnormal (US), R temporal & occipital lobe increased echogenicity; size of lesion 2×1.8×1.6 cm |
| 5 | No | 38 | 35 | 5.7/BE −15 | 5 | Brain parenchyma normal (MRI); size of lesion 2×2×2.5 cm |
| 6 | No | 3 | 2 | 5.8/BE −14 | 7 | Brain parenchyma normal (MRI); size of lesion 1.9×1.5×1.5 cm |
| 7 | Yes (36 weeks) | 5 | 5 min | 5.3/BE −13 | 4 | Brain parenchyma normal (fetal MRI,US); size of lesion 4×2×3 cm |
| 8 | Yes (38 weeks) | 48 | 28 | 7.2/BE −7.2 | 7 | Brain parenchyma normal (MRI,US); size of lesion 2.5×2.5×2 cm |
| 9 | Yes (32 weeks) | 0.2 | 15 min | 7.29/BE −6 | 8 | Brain parenchyma normal (fetal MRI); size of lesion 2×1.1×2.8 cm |