Variable | No of infants | IVH | p Value | ||||
---|---|---|---|---|---|---|---|
No | % | ||||||
Total | 2794 | 374 | 13.4 | ||||
Tocolysis | |||||||
No therapy | 2013 | 303 | 15.1 | ||||
Magnesium sulphate | 341 | 34 | 10.0 | <0.01 | |||
Ritodrine | 263 | 14 | 5.3 | ||||
Indomethacin | 177 | 23 | 13.0 | ||||
Antenatal steroid therapy | |||||||
Full | 1161 | 76 | 6.6 | ||||
Partial | 489 | 68 | 13.9 | <0.01 | |||
None | 1133 | 228 | 20.1 | ||||
Multiple birth | |||||||
Yes | 1159 | 127 | 10.0 | <0.01 | |||
No | 1635 | 247 | 15.1 | ||||
PROM (>6 hours) | |||||||
Yes | 932 | 102 | 10.0 | 0.01 | |||
No | 1856 | 270 | 14.6 | ||||
Amnionitis | |||||||
Yes | 329 | 53 | 16.1 | 0.13 | |||
No | 2461 | 321 | 13.0 | ||||
Delivery | |||||||
Vaginal | 1097 | 187 | 17.1 | <0.01 | |||
Caesarean section | 1697 | 187 | 11.0 | ||||
Gestational age (weeks) | |||||||
24–25 | 293 | 106 | 36.2 | ||||
26–27 | 614 | 123 | 20.0 | <0.01 | |||
28–29 | 871 | 126 | 12.2 | ||||
⩾30 | 1016 | 39 | 3.8 | ||||
Birth weight (g) | |||||||
>750 | 290 | 83 | 28.6 | ||||
750–999 | 703 | 136 | 19.4 | <0.01 | |||
1000–1249 | 890 | 92 | 10.1 | ||||
⩾1250 | 971 | 63 | 6.5 | ||||
SGA | |||||||
Yes | 315 | 40 | 12.7 | 0.70 | |||
No | 2479 | 334 | 13.5 | ||||
One minute Apgar score | |||||||
0–3 | 506 | 127 | 25.1 | ||||
4–7 | 1159 | 167 | 14.4 | <0.01 | |||
⩾8 | 1070 | 64 | 6.0 | ||||
Five minute Apgar score | |||||||
0–3 | 59 | 20 | 33.9 | ||||
4–7 | 556 | 119 | 20.4 | <0.01 | |||
⩾8 | 2071 | 211 | 10.2 | ||||
RDS | |||||||
Yes | 1799 | 344 | 19.1 | <0.01 | |||
No | 995 | 30 | 3.0 | ||||
PDA | |||||||
Yes | 797 | 170 | 21.3 | <0.01 | |||
No | 1996 | 204 | 10.2 | ||||
Mechanical ventilation | |||||||
Yes | 1997 | 365 | 18.3 | <0.01 | |||
No | 797 | 9 | 1.1 | ||||
Pneumothorax | |||||||
Yes | 235 | 72 | 30.6 | <0.01 | |||
No | 2559 | 302 | 11.8 | ||||
Sepsis | |||||||
Yes | 979 | 147 | 15.0 | 0.06 | |||
No | 1815 | 227 | 12.5 |
PVH, Periventricular haemorrhage; IVH, intraventricular haemorrhage; PROM, premature rupture of the membranes; SGA; small for gestational age; RDS, respiratory distress syndrome; PDA, patent ductus arteriosus.