Patient characteristics
| Fluticasone (n=15) | Placebo (n=15) | |
|---|---|---|
| Results expressed as median (interquartile range). | ||
| OFC, occipitofrontal circumference; PIP, peak inspiratory pressure; Fio2, fractional inspired oxygen. | ||
| Male | 8 (53%) | 9 (60%) |
| Gestation (wk) | 27 (25 to 28) | 28 (27 to 30) |
| Birth weight (g) | 864 (755 to 1058) | 1120 (820 to 1430) |
| Z score | 0.17 (−0.43 to 0.84) | −0.21 (−0.45 to 0.57) |
| Birth OFC (cm) | 25.2 (23.8 to 30) | 26.2 (23.5 to 28.6) |
| Z score | 0.24 (−1.18 to 1.17) | 0.06 (−0.95 to 0.50) |
| Respiratory support | ||
| Total ventilated days | 17 (13 to 34) | 15 (7 to 25) |
| Maximum PIP (cmH2O) | 25 (20 to 28) | 26 (20 to 32) |
| Maximum (Fio2 (%) | 71 (55 to 100) | 100 (70 to 100) |
| Characteristics at recruitment | ||
| Age (corrected weeks) | 39 (38 to 43) | 40 (37 to 42) |
| Weight (g) | 2458 (2100 to 2870) | 2390 (2042 to 2637) |
| Z score | −1.57 (−3.05 to −1.01) | −1.76 (−2.70 to −1.27) |
| OFC (cm) | 33.6 (32.2 to 35.5) | 33.5 (32.4 to 34.0) |
| Z score | −0.55 (−2.46 to 0.78) | −0.77 (−1.56 to 0.29) |
| Supplemental oxygen (l/min) | 0.25 (0.1 to 0.4) | 0.15 (0.05 to 0.3) |