Table 2

Results of blood transfusion and body iron status of the infants studied (n=17)

Patient noTotal volume of blood transfused (ml)Net volume of blood transfused (ml)Serum iron (μmol/l)TIBC (μmol/l)% SaturationSerum ferritin (pmol/l)Liver iron concentration (μmol/g (mg/g) dry weight)Liver histologyCause of death and relevant clinical details
Grade (0–4)Kupffer cellsHepatocytes
Group A (n=9): infants receiving <100 ml of blood
 182.61228432998.3  (0.5)0RDS
 2115.1615401266.3 (0.4)0RDS
 33213.716237090215.4 (0.9)0RDS, air embolism
 43529.31338343528.8 (0.5)0RDS
 52015.01329452978.6 (0.5)0RDS
 65127.916141142 33030.5 (1.7)2++RDS, Aplasia cutis congenita
 76237.414168867816.4 (0.9)1+RDS
 86046.86610048824.5 (1.4)1+Severe intraventricular haemorrhage
 96726.4121210010 77217.1 (1.0)1+RDS
Group B (n=8): infants receiving ⩾100 ml of blood
 10370234.82442572 80964.3 (3.6)2++BPD, cholestatic jaundice
 11171107.91726654 84017.1 (1.0)1+RDS
 1218098.126426244 88028.2 (1.6)1+NEC, cholestatic jaundice
 1313343.01922862 20014.2 (0.8)0Severe intraventricular haemorrhage
 1421393.511215211 72643.2 (2.4)1+NEC, septicaemia
 152-150 480293.2222210020 79069.4 (3.9)3++++BPD, cholestatic jaundice
 162-150 1034616.04851949 30699.8 (5.6)3++++BPD
 1718835.02532783 036168.3 (9.4)2+++Pulmonary hypoplasia, ? Larsen's syndrome
  • 2-150 Double volume exchange transfusion.

  • TIBC, total iron binding capacity; RDS, respiratory distress syndrome; BPD, bronchopulmonary dysplasia; NEC, necrotising enterocolitis.