Comparing infants receiving <100 ml of blood transfusion (group A) with those receiving ⩾100 ml (group B)
|
Group A (n=9) |
Group B (n=8) | |
| Gestational age (weeks) | 25.4 (22.9–26.8) | 28.7 (24.2–31.1) |
| Birth weight (g) | 705 (595–808) | 923 (728–1295) |
| Sex (male:female) | 6 : 2 | 3 : 5 |
| Temperature on admission (°C) | 35.9 (35.3–36.1) | 35.9 (35.3–36.3) |
| Apgar scores: | ||
| at 1 minute | 4 (2–6.5) | 5.5 (3–8) |
| at 5 minute | 6 (6–8.5) | 8 (7.25–9) |
| Mode of delivery (vaginal:caesarean section) | 6 : 3 | 5 : 3 |
| Severity of RDS | ||
| Grade 1–2 (n) | 1 | 1 |
| Grade 3–4 (n) | 8 | 7 |
| Duration of mechanical ventilation (days) | 1 (1–7) | 64 (17–107)** |
| Duration of O2 supplementation (days) | 1 (1–7) | 63 (17–109)** |
| Duration of hospital stay (days) | 1 (1–7) | 83 (34–138)** |
| Total volume of blood transfused (ml) | 35 (18–61) | 201 (173–453)** |
| Net volume of blood transfused (ml) | 26 (12–31) | 103 (56–279)** |
| Patients required exchange transfusion (n) | 0 | 2 |
| Dry weight of liver biopsy (mg) | 20 (15–30) | 18 (17–20) |
| Serum iron concentration (μmol/l) | 13.0 (10.5–14.5) | 23.0 (17.5–25.8)1-150 |
| Total iron binding capacity (μmol/l) | 16.0 (13.5–28.3) | 29.0 (22.0–42.0) |
| % Saturation | 70.0 (42.3–100.0) | 71.5 (58.3–92.0) |
| Serum ferritin concentration (pmol/l) | 488 (299–1259) | 7073 (2866–18524)1-150 |
| Liver iron concentration | ||
| (μmol/g dry weight) | 15.4 (8.5–19.0) | 53.8 (19.9–92.2)1-150 |
| (mg/g dry weight) | 0.90 (0.50–1.10) | 3.00 (1.15–5.18)1-150 |
| Semiquantitative histological liver iron grading (n)1-150 | ||
| Grade 0 | 5 | 1 |
| Grade 1 | 3 | 3 |
| Grade 2 | 1 | 2 |
| Grade 3 | 0 | 2 |
| Grade 4 | 0 | 0 |
Results are number of patients or median (interquartile range). The duration of hospital stay is the same as the age of death.
↵1-150 p<0.05 and **p<0.001.
RDS, respiratory distress syndrome.