Table 2

Plasma concentrations of total, free, and bound leptin, and percentage of free leptin at birth and at 3 days of age, in infants born to either mothers with gestational diabetes mellitus (GDM) or healthy mothers

Infants of GDM mothers Infants of healthy mothers
Leptin concentration in cord plasma (μg/l)
 Total15.0  (3.2–43.8)2-150 7.2  (2.4–26.8)
 Free8.5 (1.8–27.2)2-150 3.4 (1.1–13.9)
 Bound5.5 (1.4–16.6)2-150 3.5 (1.4–12.9)
Percentage of free leptin58.7 (49.1–70.0)2-150 52.6 (40.6–57.5)
Leptin concentration at 3 days of age (μg/l)
 Total1.8 (1.0–3.7)2-151 1.7 (0.6–2.6)2-151
 Free1.0 (0.5–1.9)2-151 0.9 (0.5–1.2)2-151
 Bound0.8 (0.5–1.8)2-151 0.8 (0.6–1.4)2-151
Percentage of free leptin55.3 (49.6–67.7)2-150 50.4 (44.5–56.2)2-164
  • Values are median (range).

  • 2-150 p < 0.05 compared with infants of healthy mothers.

  • 2-151 p < 0.005 compared with at birth.

  • 2-164 p < 0.05 compared with at birth.