Effect of colonisation time with Bacteroides fragilis group bacteria on the number of IgA-secreting and IgM-secreting cells in peripheral blood at 2 and 6 months of age
| B fragilis colonisation | p Value3-150 | ||||
|---|---|---|---|---|---|
| Before 1 month of age (n=15) | At 1–2 months of age (n=5) | At 2–6 months of age (n=7) | Never during the study period (n=13) | ||
| Number of ISCs at 2 months | |||||
| IgA | 1410 (953 to 2087) | 1809 (1029 to 3180) | 1289 (710 to 2340) | 814 (602 to 1100) | 0.048 |
| IgM | 631 (303 to 1319) | 781 (324 to 1883) | 505 (310 to 823) | 360 (221 to 587) | 0.39 |
| Number of ISCs at 6 months | |||||
| IgA | 1511 (1186 to 1925) | 2429 (979 to 6023) | 1249 (723 to 2158) | 1286 (799 to 2071) | 0.26 |
| IgM | 788 (470 to 1321) | 2288 (436 to 12001) | 885 (488 to 1603) | 461 (307 to 692) | 0.012 |
Data are given as geometric mean with 95% confidence interval of immunoglobulin-secreting cells (ISCs)/106 mononuclear cells.
↵3-150 Analysis of variance; overall difference between groups of infants colonised at different time points.