Effect of intestinal colonisation with Bacteroides fragilis group bacteria at 1 month of age, and type of feeding on the number of IgA-secreting, IgG-secreting, and IgM-secreting cells and the total number of immunoglobulin-secreting cells (ISCs) in peripheral blood at 2 months of age in healthy infants
| Colonised | Non-colonised | ||||||
|---|---|---|---|---|---|---|---|
| Formula fed (n=7) | Breast fed (n=12) | Formula fed (n=14) | Breast fed (n=22) | ||||
| Isotype of ISC | |||||||
| IgA2-150 | 2238 (1334 to 3754) | 1057 (624 to 1789) | 1013 (659 to 1558) | 1016 (806 to 1280) | |||
| IgG2-151 | 1400 (435 to 4495) | 928 (628 to 1372) | 908 (592 to 1394) | 727 (550 to 961) | |||
| IgM2-152 | 1352 (372 to 4915) | 520 (266 to 1014) | 425 (276 to 655) | 376 (264 to 534) | |||
| Total number of ISCs2-153 | 5911 (2233 to 15644) | 2628 (1832 to 3770) | 2503 (1664 to 3767) | 2281 (1841 to 2826) | |||
Data are given as geometric mean with 95% confidence interval of ISCs/106 mononuclear cells.
↵2-150 Two way analysis of variance: p=0.04 for colonisation and p=0.06 for type of feeding; interaction p=0.06.
↵2-151 Two way analysis of variance: p=0.12 for colonisation and p=0.15 for type of feeding; interaction p=0.66.
↵2-152 Two way analysis of variance: p=0.009 for colonisation and p=0.05 for type of feeding; interaction p=0.13.
↵2-153 Two way analysis of variance: p=0.01 for colonisation and p=0.02 for type of feeding; interaction p=0.06.