Haemolysis in test solutions compared with 0.25% normal saline
| Solution tested | No of patients | Haemolysis (%) | Difference in % haemolysis, 0.25% NS—comparison solution | Paired t test (2 sided p value)3-150 | |||||
|---|---|---|---|---|---|---|---|---|---|
| 0.25% NS | Solution tested | ||||||||
| NS | 11 | 5.434 (0.372) | 0.070 (0.016) | 5.364 (0.363) | <0.001 | ||||
| IAA | 4 | 5.967 (0.476) | 0.889 (0.142) | 5.078 (0.605) | 0.004 | ||||
| D5W | 8 | 5.500 (0.503) | 1.029 (0.059) | 4.471 (0.462) | <0.001 | ||||
| 0.5 % NS | 4 | 5.967 (0.476) | 0.888 (0.322) | 5.079 (0.292) | <0.001 | ||||
| IAA + cysteine | 4 | 5.967 (0.476) | 0.655 (0.125) | 5.312 (0.375) | 0.001 | ||||
| Isotonic sodium acetate | 4 | 5.967 (0.476) | 0.105 (0.039) | 5.862 (0.439) | 0.001 | ||||
| TPN + lipids | 4 | 5.967 (0.476) | 1.157 (0.208) | 4.81 (0.549) | 0.003 | ||||
| IAA + cysteine + minerals + vitamins | 4 | 5.967 (0.476) | 0.621 (0.130) | 5.346 (0.377) | 0.001 | ||||
| D5 0.25% NS | 4 | 5.967 (0.476) | 0.856 (0.158) | 5.111 (0.321) | 0.001 | ||||
| 0.25% NS drawn up slowly | 7 | 5.129 (0.506) | 5.774 (0.331) | −0.645 (0.480) | 0.227 | ||||
| 0.25% NS mixed completely | 7 | 5.423 (0.441) | 3.052 (0.232) | 2.371 (0.247) | <0.001 | ||||
| 0.25% NS drawn up slowly and mixed completely | 7 | 5.129 (0.506) | 3.532 (0.431) | 1.597 (0.266) | 0.001 | ||||
Values are expressed as mean (SEM).
↵3-150 For the paired t test, the analysis was based on the paired differences and only patients who had both sets of measurements contributed to the analysis.
NS, normal saline; D5W, isotonic dextrose; IAA, isotonic amino acids; TPN, total parenteral nutrition; D5 0.25% NS, 5% dextrose in 0.25% normal saline.