Table 1

Comparison between single perinatal variables

SNHL group (n = 15)Comparison group (n = 30)Likelihood ratio test
MedianRangeMedianRange
Birth weight (g)960600–29141026410–2814p = 0.667
Apgar score
At 1 min51–85.51–9p = 0.216
 At 5 min82–98.53–10p = 0.156
CRIB score41–920–12p = 0.512
n = 14n = 28(14 matched sets)
Maximum serum bilirubin (μmol/l)1-151 239148–473232.5130–366p = 0.174
Duration of
Intubation (days)144–4120–48p = 0.0111-150
 Respiratory support (days)1-152 349–935.50–67p = 0.0021-150
 Added O2 (days)572–1409.50–120p = 0.0041-150
 pH < 7.2 (h)120–850.50–28.5p = 0.0011-150
 Base excess <−9.0 (h)90–5700–58p = 0.0341-150
Netilmicin n = 13n = 24(13 matched sets)
 Peak (mg/l)6.65.4–106.42.9–9.4p = 0.357
(11 matched sets)
 Trough (mg/l)2.51.2–4.92.30.6–5.2p = 0.252
Vancomycin n = 4n = 4(1 matched sets)
 Peak (mg/l)34.319.3–43.125.717.8–46.8 1-154
 Trough (mg/l)13.853.5–186.25.2–20.9 1-154
n % n % Odds ratio (95% CI)
Received ventilation138722732.3 (0.4–12.2)
Positive blood culture117314477.0 (0.8–60.2)1-150
Bilirubin > 200 μmol/l1-153 12/148622/28792.0 (0.4–10.6)
Bilirubin > GA × 101-153 2/14144/28141.0 (0.2–5.5)
Creatinine > 60 mmol/l12/14861860 1-154
Treated with
Dopamine533275.0 (1.0–25.8)1-150
 Frusemide138716539.7 (1.2–81.8)1-150
 Indomethacin4278271.0 (0.2–4.3)
 Netilmicin151002687 1-154
 Vancomycin6405174.0 (0.8–20.9)
Abnormal cerebral ultrasound scan106741315.6 (2.0–124.3)1-150

  • ↵1-150 p < 0.05 on likelihood ratio test, including positive blood culture, as 95% CI values are approximate.

  • ↵1-151 No bilirubin results were available for one index and two control children (14 matched sets).

  • ↵1-152 Includes continuous positive airways pressure.

  • ↵1-153 Arbitrary exchange level = bilirubin concentration > gestational age × 10.

  • ↵1-154 Convergence not possible, neither significant using Fisher's exact test (does not take account of matching).