Clinical characteristics of study neonates
| CLD (n=13) | non-CLD (n=11) | |
|---|---|---|
| Gestational age (weeks) | 27 (24-29) | 28 (26-30) |
| Birthweight (g) | 1065 (694-1320) | 1168 (626-1408) |
| Male | 9/13 | 6/11 |
| Fetal distress | 5/13 | 3/11 |
| Caesarean section | 10/13 | 8/11 |
| Apgar score | ||
| At 1 min | 5 (1-8) | 6 (1-8) |
| At 5 min | 7 (2-10) | 9 (1-10) |
| Surfactant therapy | 11/13 | 7/11 |
| HFO/IMV | 8/5 | 7/4 |
| Mean ventilator airway pressure (cm H2O) | 13 (8-15) | 13 (10-15) |
| Total extra oxygen supplementation (% hours) | ||
| Within 24 hours | 674 (226-906) | 566 (23-1616) |
| Within 7 days | 2071 (371-5252) | 1257 (68-5002) |
| Duration of intubation (days) | 10 (4-83)1-150 | 4 (1-20) |
| Extubation by 7 days of life | 2/13 | 4/11 |
| Duration of oxygen supplementation (days) | 61 (38-126)1-150 | 10 (1-64) |
| Duration of phototherapy within 7 days of life (hours) | 48 (0-144) | 36 (0-111) |
| Urine output (ml/kg/h) | ||
| Day 0 | 1.4 (0.3-2.7) | 0.8 (0.2-2.7) |
| Days 4-6 | 2.9 (2.3-5.6) | 3.4 (2.3-4.5) |
| Age at the beginning of enteral feeding (days) | 8 (4-25) | 6 (3-10) |
| Start of enteral feeding by 7 days of life | 5/13 | 5/11 |
Values are expressed as median and range. Differences between groups are assessed by Mann-Whitney U-test or Fisher’s exact test as appropriate.
↵1-150 p<0.05 vs non-CLD infants.