Screened (n=60) | Non-screened (n=57) | p Value | |
---|---|---|---|
Male:female | 34:26 | 29:28 | 0.5 |
Meconium ileus | 7 | 6 | 0.8 |
Age of diagnosis (months) | |||
Median (range) | 1.8 (0.1-81.0) | 5.7 (0.1-51.5) | <0.0001 |
Excluding meconium ileus | 1.8 (0.1-81.0) | 6.2 (1.1-51.5) | <0.0001 |
Excluding 3 patients missed by screening (n=57) | 1.8 (0.1-7.6) | ||
Pancreatic function | |||
PS:PI at diagnosis | 16:44 | 6:51 | 0.03 |
PS becoming PI | 10 | 3 | 0.6 |
Symptoms at diagnosis (including meconium ileus) | 30 | 56 | <0.0001 |
Height SDS at diagnosis | |||
Combined mean (SD) | −0.2 (1.6) | −1.2 (1.6) | 0.006 |
Pancreatic sufficient [PS] | −0.4 (1.4) | −0.06 (0.9) | |
Pancreatic insufficient [PI] | −0.2 (1.7) | −1.4 (1.7) | |
Weight SDS at diagnosis | |||
Combined mean (SD) | −0.1 (1.4) | −1.2 (1.4) | <0.0001 |
Pancreatic sufficient [PS] | 0.3 (0.9) | 0.1 (0.9) | |
Pancreatic insufficient [PI] | −0.2 (1.6) | −1.3 (1.3)* | |
Deaths due to CF | 1 | 4 | 0.2 |
Total lost to follow up (includes deaths and transfers) | 10 | 17 | 0.1 |
SDS = standard deviation score; SD = standard deviation; Students t test: * p<0.01 for difference in SDS between PS and PI.