Table 5

Chronic lung disease: high frequency ventilation (HFV) versus conventional ventilation (CV)

ReferenceHFV event observed/ total No of patientsCV event observed/ total No of patientsRelative risk (95% CI)
Clark, 19923/3010/260.26 (0.08, 0.84)
Wiswell, 19966/377/360.83 (0.31, 2.24)
Keszler, 199711/5521/520.50 (0.27, 0.92)
Rettwitz-Volk, 19980/460/50Not estimable
Plavka (in press)4/218/200.48 (0.17, 1.34)
Total for all studies24/18946/1840.49 (0.32, 0.75)
Total for HLVS subgroup18/10639/980.43 (0.26, 0.70)
Total for surfactant subgroup21/15936/1580.56 (0.35, 0.89)
Total for HFOV subgroup7/9718/960.35 (0.16, 0.77)
Total for HFJV subgroup17/9228/880.58 (0.34, 0.98)
  • HFV=high frequency ventilation; HFOV=high frequency oscillatory ventilation; HFJV=high frequency jet ventilation; CV=conventional ventilation; RDS=respiratory distress syndrome; BPD=bronchopulmonary dysplasia; CLD=chronic lung disease; HLVS=high lung volume strategy; RR=relative risk; CI=confidence interval.