Reference | HFV event observed/ total No of patients | CV event observed/ total No of patients | Relative risk (95% CI) |
---|---|---|---|
Clark, 1992 | 3/30 | 10/26 | 0.26 (0.08, 0.84) |
Wiswell, 1996 | 6/37 | 7/36 | 0.83 (0.31, 2.24) |
Keszler, 1997 | 11/55 | 21/52 | 0.50 (0.27, 0.92) |
Rettwitz-Volk, 1998 | 0/46 | 0/50 | Not estimable |
Plavka (in press) | 4/21 | 8/20 | 0.48 (0.17, 1.34) |
Total for all studies | 24/189 | 46/184 | 0.49 (0.32, 0.75) |
Total for HLVS subgroup | 18/106 | 39/98 | 0.43 (0.26, 0.70) |
Total for surfactant subgroup | 21/159 | 36/158 | 0.56 (0.35, 0.89) |
Total for HFOV subgroup | 7/97 | 18/96 | 0.35 (0.16, 0.77) |
Total for HFJV subgroup | 17/92 | 28/88 | 0.58 (0.34, 0.98) |
HFV=high frequency ventilation; HFOV=high frequency oscillatory ventilation; HFJV=high frequency jet ventilation; CV=conventional ventilation; RDS=respiratory distress syndrome; BPD=bronchopulmonary dysplasia; CLD=chronic lung disease; HLVS=high lung volume strategy; RR=relative risk; CI=confidence interval.