Table 2

Plasma ACTH and serum cortisol concentrations before and after hCRH stimulation at days 7 and 14 in preterm infants whose mothers received eight or more doses of antenatal dexamethasone

ACTH (pmol/l)Cortisol (nmol/l)
0 min15 mins30 mins60 mins0 min15 mins30 mins60 mins
Day 7 (n = 14)5.1  (0.7)11.5  (2.3)8.4  (1.4)6.3  (0.9)283  (47)450  (44)552  (60)347  (64)
Day 14 (n = 12)7.9 (1.1)12.0 (2.4)10.2 (1.6)8.3 (1.3)371 (33)453 (46)552 (56)374 (50)
Differences between days 14 and 7 (n = 12)2.4 (1.3)2.1 (2.3)2.8 (1.3)2.6 (1.1)62 (61)-12 (78)-20 (86)25 (96)
  • Values are mean (SEM)