Table 1

Characteristics of trials incuded in this review

ReferenceHFV typeVentilator typeHLVS*SurfactantNo of patientsMean birthweight (kg)Mean gestational age (weeks)Mean age HFV started (hours)
Froese, 1987 16 HFOVHSMVB, (Metrex Instruments)NoNo151.1 (0.8)28 (1)Not reported
HIFI, 1989 6 HFOVHummingbird, (Senko Medical Instrument Manufacturing)NoNo6731.1 (0.3)28 (2)6 (0.5)
Carlo, 1990 17 HFJVSelf constructed NoNo421.4 (0.3)30 (2)15 (4-30)
Clark, 1992 7 HFOVSensormedics 3100, (Sensormedics)YesNo831.1 (0.3)28 (3)9 (5)
Ogawa, 1993 8 HFOVHummingbird BMO 20 N, (Senko Medical Instruments Manufacturing)YesYes921.2 (0.3)29 (2)2 (2)
Gerstmann, 1996 9 HFOVSensormedics 3100 (A), (Sensormedics)YesYes1251.5 (0.5)31 (2)3 (1)
Wiswell, 1996 23 HFJVLife Pulse HFJV, (Bunnell Inc)NoYes730.9 (0.3)27 (2)7 (5)
Keszler, 1997 10 HFJVLife Pulse HFJV (Bunnell Inc)YesYes1301.0 (0.2)27 (2)8 (4)
Rettwitz-Volk 25 HFOVStephan SHF 3000,
(F Stephan Medizintechnik)
NoYes961.1 (0.1)28 (1)1 (0.5)
Plavka 11 (in press)HFOVSensormedics 3100A (Sensormedics)YesYes430.85 (0.2)26 (2)Not reported
  • All values are expressed as mean (SD); * HLVS: high lung volume strategy; as described by Carlo WA et al in J Pediatr 1984;104:101-7 and by Carlon GC et al in Crit Care Med 1981;9:47-50. Value expressed as mean (range); Ventilatory stabilisation on assigned ventilator mode according to the protocol within 3 hours after birth. HFV=high frequency ventilation; HFOV=high frequency oscillatory ventilation; HFJV=high frequency jet ventilation; CV=conventional ventilation; RDS=respiratory distress syndrome; BPD=bronchopulmonary dysplasia; CLD=chronic lung disease; HLVS=high lung volume strategy; RR=relative risk; CI=confidence interval.