Table 1

Demographic characteristics of study and control infants: numbers are given in mean (SEM) or absolute numbers (%)

Group 1 (fluticasone) n=27Group 2 (placebo) n=26p Value
Gestation (week) 27.9 (0.5)27.1 (0.5)0.2751-150
Birthweight (g) 993 (71)981 (71)0.9061-150
Complications of pregnancy 0.186**
 Nil17 (63.0)23 (88.5)
 Diabetes mellitus4 (14.8)1 (3.8)
 Infection2 (7.4)1 (3.8)
 Antepartum haemorrhage4 (14.8)1 (3.8)
Multiple pregnancy 0.701**
 Twin6 (22.2)8 (30.8)
 Triplet2 (7.4)1 (3.8)
Rupture of amniotic membrane
 Duration (h) 11.0 (1.3)13.8 (2.5)0.3301-150
 Duration > 24 h 0 (0.0)3 (11.5)0.111**
Antenatal corticosteroid 15 (55.6)13 (50.0)0.897**
Mode of delivery 0.785**
 Spontaneous vaginal12 (44.4)11 (42.3)
 Breech vaginal3 (11.1)3 (11.5)
 Forceps1 (3.7)0 (0.0)
 Caesaerean section11 (40.7)12 (46.2)
Apgar score at 5 min < 7 8 (29.6)8 (30.8)0.835**
Peak inflation pressure at enrolment 21.2 (0.8)20.5 (0.6)0.4631-150
PaO2: alveolar PO2 ratio at enrolment 0.19 (0.01)0.19 (0.01)0.6301-150
  • 1-150 Student’s t test, **χ2 test.