Serum 25(OH)D and 1,25(OH)2D concentrations in preterm infants at different ages receiving either high or low vitamin D doses
| Group A 200 IU/kg of body weight/ day up to 400 IU/day | Group B 960 IU/day | ||||||
|---|---|---|---|---|---|---|---|
| n | Mean (SD) | n | Mean (SD) | Mean difference (95% CI) | |||
| 25(OH)D from umbilical cord | 6 | 29.8 (10.0) | 8 | 29.2 (11.8) | 0.6 (−12.5 to 13.7) | ||
| chronological age 6 weeks | 15 | 45.7 (18.4) | 11 | 66.7 (30.3) | −21.0 (−40.7 to −1.3) | ||
| chronological age 12 weeks | 10 | 79.1 (30.0) | 6 | 113.5 (37.7) | −34.4 (−70.8 to 2.1) | ||
| corrected age 3 months | 9 | 87.0 (18.1) | 16 | 93.4 (36.4) | −6.4 (−25.7 to 12.8) | ||
| corrected age 6 months | 19 | 86.4 (23.9) | 16 | 90.2 (26.8) | −3.8 (−21.3 to 13.6) | ||
| 1,25(OH)2D from umbilical cord | 6 | 43.8 (21.5) | 8 | 69.2 (25.6) | −25.8 (−53.6 to 2.8) | ||
| chronological age 6 weeks | 13 | 120.5 (64.7) | 11 | 138.8 (62.0) | −18.3 (−72.3 to 35.6) | ||
| chronological age 12 weeks | 9 | 178.0 (66.8) | 6 | 160.2 (79.8) | 17.8 (−64.3 t o 100.0) | ||
| corrected age 3 months | 16 | 150.1 (46.6) | 15 | 135.6 (55.9) | 14.4 (−23.2 to 52.2) | ||
| corrected age 6 months | 19 | 110.2 (28.2) | 15 | 162.3 (39,6) | −52.2 (−75.7 to −28.4) | ||