Mean (SD) bile acids in faeces of healthy infants
| Bile acid (μmol/g) | 0 days (n=5) | 7 days (n=6) | 1 month (n=2) | 3 months (n=5) |
|---|---|---|---|---|
| Usual bile acids | 4.31 (3.55)3-a | 1.35 (0.29) | 1.70 (0.17) | 1.94 (0.61) |
| % in total bile acids | (27.64 (9.81)) | (21.52 (6.47)) | (29.36 (7.75)) | (31.36 (13.88)) |
| Fetal bile acids | 4.41 (1.94)b | 1.99 (0.60) | 2.39 (0.95) | 2.69 (1.29) |
| % in total bile acids | (32.65 (11.06)) | (31.68 (11.35)) | (39.68 (9.32)) | (38.33 (11.05)) |
| Ursodeoxycholic acid | 0.31 (0.09) | 0.36 (0.18) | 0.23 (0.01) | 0.32 (0.09) |
| % in total bile acids | (2.41 (0.92)a c) | (5.23 (1.44)) | (3.86 (0.54)) | (5.42 (3.32)) |
| 3-oxo-Δ1 bile acid | 0.93 (0.54) | 0.70 (0.32) | 0.82 (0.02) | 0.66 (0.25) |
| % in total bile acids | (6.44 (1.47)a c d) | (10.59 (3.10)) | (14.01 (2.77)c) | (9.72 (1.67)) |
| 3-oxo-Δ4 bile acids | 4.27 (2.10)a e f | 2.29 (1.63) | 0.79 (0.23) | 1.07 (0.51) |
| % in total bile acids | (30.86 (16.28)) | (30.98 (14.97)) | (13.09 (1.73)) | (15.17 (5.01)) |
| Total bile acids | 14.22 (6.86)b e f | 6.69 (2.07) | 5.92 (1.00) | 6.67 (1.67) |
Usual bile acids: CA, CDCA, DCA, LCA. Fetal bile acids: CA-1β-ol, CDCA-1β-ol, HCA, Δ5-3β-ol. 3-oxo-Δ1 bile acid: Δ1-3-one. 3-oxo-Δ4 bile acids: Δ4-3-one, Δ4, 6-3-one.
↵3-a P < 0.05 vs 7 days; b P < 0.01vs 7 days; c P < 0.05 vs 3 months; d P < 0.01 vs 1 month; eP < 0.05 vs 1 month, f P < 0.01vs 3 months .