Table 2

Mean (SD) bile acids in urine of healthy infants

Bile acid (μmol/mmol Cr)	0 days (n=6)	3 days (n=6)	7 days (n=6)	1 month (n=6)	2 months (n=6)	3 months (n=6)
Usual bile acids	0.40 (0.19)^a b	2.69 (2.67)	1.84 (1.24)	3.47 (1.83)	1.96 (0.74)^c	1.12 (0.37)
% in total bile acids	(14.19 (5.74)^c d e)	(13.60 (7.82)^c d f)	(17.36 (8.43)^b g)	(29.10 (5.45))	(23.19 (2.75))	(25.61 (3.86))
Fetal bile acids	0.54 (0.19)^b h i	6.26 (3.81)^g	5.59 (3.55)	6.29 (6.21)^g	3.87 (1.64)	1.93 (0.70)
% in total bile acids	(18.63 (5.86)^{a b c j k})	(35.95 (19.02))	(41.40 (16.34))	(44.66 (11.42))	(45.96 (10.01))	(43.88 (5.40))
Ursodeoxycholic acid	0.04 (0.02)^b c f	0.08 (0.04)^b e g	0.14 (0.07)^b	0.35 (0.18)	0.27 (0.10)	0.29 (0.24)
% in total bile acids	(1.48 (0.92)^e l m)	(0.52 (0.33)^b f m)	(1.99 (1.77)^m)	(3.25 (1.47)^c)	(3.45 (1.36)^c)	(5.90 (1.98))
3-oxo-Δ¹ bile acid	1.09 (0.88)^2-a	6.94 (4.83)^e g l	5.63 (8.89)^e g	0.79 (0.37)	0.54 (0.21)	0.35 (0.12)
% in total bile acids	(31.44 (17.24)^d k m)	(34.57 (18.00)^d k m)	(22.93 (9.55)^e g l)	(6.81 (1.76))	(6.60 (2.00))	(8.17 (1.68))
3-oxo-Δ⁴ bile acids	1.15 (1.05)	3.27 (3.15)	6.26 (13.75)	2.00 (1.38)	1.81 (1.24)	0.81 (0.62)
% in total bile acids	(34.27 (16.22)^{g h i l})	(15.36 (9.30))	(16.32 (17.19))	(16.18 (5.33))	(20.80 (11.76))	(16.44 (4.48))
Total bile acids	3.22 (1.86)^a i	19.24 (8.93)^g	19.46 (24.81)^g	12.91 (9.46)	8.45 (2.88)	4.50 (1.93)

Usual bile acids: CA, CDCA, DCA, LCA. Fetal bile acids: CA-1β-ol, CDCA-1β-ol, HCA, Δ⁵-3β-ol. 3-oxo-Δ¹ bile acid: Δ¹-3-one. 3-oxo-Δ⁴ bile acids: Δ⁴-3-one, Δ^{4, 6}-3-one.
↵2-a P < 0.05 vs 3 days; ^b P < 0.01vs 1 month; ^c P < 0.01 vs 3 months; ^d P < 0.001 vs 1 month; ^eP < 0.05 vs 2 months, ^f P < 0.01vs 2 months; ^g P < 0.05 vs 3 months; ^h P < 0.01 vs 3 days; ⁱ P < 0.05 vs 7 days; ^j P < 0.01 vs7 days; ^k P < 0.001 vs 2 months,^l P < 0.05 vs 1 month; ^m P < 0.001 vs 3 months.