Table 1

Sex, age at onset, initial symptoms, cystic location, genetic risk factors, age at final diagnosis, outcome and family history in children with porencephaly

Sex	Onset	Initial symptoms	Porencephalic location	Genetic risk factor	Age at final diagnosis	Outcome	Family history
M	1 day	Focal seizures	L middle cerebral artery	F V Leiden	2 years	Lennox	+
				/ Lp (a): 120 mg/dl
M	6 weeks	Seizures	L middle cerebral artery	F V Leiden	4 years	Lennox	−
M	Birth	Focal seizures	R middle cerebral artery	Protein S type I	4 weeks	Blindness death	+
				free ag: 8%; total: 10%
F	Birth	Hypotonia seizures	L middle cerebral artery	Protein C type I	S years	Lennox	−
				ac: 25%; ag 20%
M	3 years	Macrocephaly	R middle cerebral artery	Lp (a): 60 mg/dl	16 years	L hemiparesis	−
		L hemiparesis	R posterior artery
M	8 weeks	Hypotonia seizures	R/L middle cerebral artery	Lp (a): 70 mg/dl	7 years	Tetraparesis/ retardation	−
M	8 weeks	Seizures	R middle cerebral artery	Protein C type I	15 years	L hemiparesis	−
				ac: 40%; ag 45%
M	8 weeks	Focal seizures	L middle cerebral artery		14 years	L hemiparesis	−
M	5 months	Seizures	R middle cerebral artery	F V Leiden	18 years	L hemiparesis	+
		L hemiparesis		Lp (a): 145 mg/dl
M	Birth	Seizures	L middle cerebral artery	F V Leiden	3 years	R hemiparesis	+
			L posterior artery	Protein S type I		Severe retardation
				free ag: 15%, total: 20%
F	2 years	Seizures	L middle cerebral artery	Protein C type I	4 years	No handicap	−
				ac: 22%; ag: 30%
M	4 weeks	Focal seizures	L middle cerebral artery	F V Leiden	8 years	R hemiparesis	−
M	6 weeks	Focal seizures	L middle cerebral artery		10 years	R hemiparesis: mild	−
F	3 months	Focal seizures	L middle cerebral artery	Lp (a): 90 mg/dl	16 years	R hemiparesis: mild	−
M	4 months	L hemiparesis	R middle cerebral artery		6 years	L hemiparesis	−
		Seizures
M	4 months	R hemiparesis	L middle cerebral artery		10 years	R hemiparesis: mild	−
			L posterior artery
F	5 months	Tetraparesis	R/L middle cerebral artery	F V Leiden	5 years	Tetraparesis	−
		Seizures				Blindness/retardation
F	3 months	Focal seizures	L middle cerebral artery	Protein C type I	2 years	R hemiparesis	+
			L anterior artery	ac: 15%; ag: 22%		Retardation
F	8 weeks	Macrocephaly	L posterior artery		13 years	No handicap	−
		Seizures
F	Birth	Focal seizures	L middle cerebral artery	Protein C type I	12 years	R hemiparesis	−
				ac: 51%; ag: 50%		Retardation
M	4 months	R hemiparesis	L middle cerebral artery		4 years	R hemiparesis	−
		Seizures				Retardation
M	3 months	Focal seizures	L middle cerebral artery		18 years	R hemiparesis	−
						Blindness
						Retardation
F	Birth	Focal seizures	L middle cerebral artery	Protein C type I	4 years	R hemiparesis	−
				ac: 22%; ag 20%
F	4 months	Seizures	L middle cerebral artery		14 years	R hemiparesis	−
		R hemiparesis				Retardation

M=male; F=female; L=left; R=right; Lp (a)=lipoprotein (a); ac=activity; ag: antigen.