Effect of furosemide on pulmonary function in premature infants
| Measurement | Route of administration | Before mean (SE) | Minutes after mean (SE) | ||||
|---|---|---|---|---|---|---|---|
| 30 | 60 | 120 | P value | ||||
| Tidal volume (ml/kg) | Nebulised | 7.3 (0.3) | 8.0 (0.4) | 8.8 (0.5) | 9.3 (0.7) | 0.001 | |
| Intravenous | 8.2 (0.5) | 7.9 (0.5) | 8.4 (0.7) | 8.2 (0.6) | 0.7 | ||
| Compliance (ml/kg/cmH2O) | Nebulised | 0.58 (0.03) | 0.65 (0.03) | 0.73 (0.04) | 0.76 (0.06) | 0.002 | |
| Intravenous | 0.66 (0.05) | 0.65 (0.05) | 0.67 (0.07) | 0.68 (0.07) | 0.96 | ||
| Resistance (cmH2O/l/sec) | Nebulised | 103 (8.3) | 94 (8.3) | 103 (12.5) | 94 (6.1) | 0.6 | |
| Intravenous | 104 (7.0) | 125 (13.3) | 102 (5.8) | 106 (11.2) | 0.15 | ||