Heart rate, spontaneous respiratory rate, SaO2, tcPO2 and tcPCO2 within first 60 minutes after delivery of salbutamol aerosol
| Device used | Area under the curve/60 min: adjusted mean (SEM)3-154 | ||||
|---|---|---|---|---|---|
| Heart rate (beats/min) | Respiratory rate (breaths/min) | SaO2(%) | tcPO2 (mm Hg) | tcPCO2(mm Hg) | |
| Study 1: | |||||
| 1 (MDI) | 168.6 (3.6) | 43.9 (1.2) | 95.9 (0.6) | 64.1 (0.8) | 32.2 (0.8) |
| 2 (Jet) | 155.7 (3.6) | 42.7 (1.2) | 96.7 (0.6) | 61.3 (0.8) | 32.2 (0.8) |
| 3 (Ultrasonic) | 168.8 (3.6) | 42.1 (1.2) | 95.8 (0 6) | 67.7 (0.8) | 30.6 (0.8) |
| F test p3-150 | 0.0231 | 0.574 | 0.461 | 0.00012 | 0.330 |
| Study 2: | |||||
| 1 (MDI) | 156.7 (1.3) | 43.0 (1.2) | 94.8 (0.3) | 64.5 (0.5) | 30.4 (0.7) |
| 2 (Jet) | 151.6 (1.9) | 41.0 (1.2) | 95.3 (0.3) | 62.3 (0.5) | 31.9 (0.7) |
| 3 (Ultrasonic) | 168.8 (1.3) | 43 0 (1.2) | 95 4 (0.3) | 64.7 (0.5) | 28.7 (0.7) |
| F test p3-150 | 0.00013 | 0.226 | 0.477 | 0.0064 | 0.0145 |
↵3-154 Adjusted by covariance analysis with the pre-treatment values as covariance.
↵3-150 Analysis of covariance.
Multiple pairwise comparison by pairwise student t test (adjusted for number of comparison):
1 MDI vs jet: p=0.018; Jet vs ultrasonic: p=0.016.
2 MDI vs jet: p=0.022; MDI vs ultrasonic: p=0.003; Jet vs ultrasonic: p=0.0001.
3 MDI vs jet: p=0.012; MDI vs ultrasonic: p=0.024; Jet vs ultrasonic: p=0.0001.
4 MDI vs jet: p=0.007; Jet vs ultrasonic: p=0.003.
5 Jet vs ultrasonic: p=0.004.