Investigation following a neonatal seizure
| First line |
|---|
| Pulse oximetry |
| Glucose |
| Packed cell volume |
| Serum calcium (ionised if possible), sodium, magnesium |
| Arterial pH |
| Lumbar puncture, blood cultures |
| Cranial ultrasound scan |
| EEG |
| Second line |
| MRI or CT |
| Maternal and neonatal samples (urine/hair/meconium) for drugs of abuse |
| Specimens for virology and congenital infection |
| Serum ammonia, amino acids |
| Urinary amino acids and organic acids |
| Consider therapeutic trial or pyridoxine |