Table 4

Clinical data of neonates with seizures and diffuse brain injury

Case No	MRI (day)	Outcome	Perinatal risk signs	NE	Apgar (5 min)	Umbilical pH
1	D1: Heterogeneous T₂ SI of WM	^†	Pre-eclampsia FB, MF	3	2	6.73
2	D2: As pt. 1 D7: A + C	^†	Placental abruption, MF	3	3	6.85
3	D2: A + C	^†	FB, MA, MF	3	6	6.76
4	D27: C	CP	MF	3	3	6.90
5	D30: C + E	CP	MF	3	4	6.81
6^*	D4: A + E + SAH	CP	FB, MSA	2	10	7.16
7^*	D2: A + C	CP	FB	3	9	7.10
8^*	D28: D + C	CP	FB, MSA	2	9	7.30
9^*	D4: B + C	^†	None	2	10	7.19
10^*	D4: CNS malformation	^†	Floppy	2	9	7.32
11^*	D4: CNS malformation	^†	Floppy	2	9	7.32
12^*	D7: CNS malformation	^†	Microcephalic MSA	2	10	NA

MRI patterns A-E are described in table 1.
NE = neonatal encephalopathy according to Sarnat¹⁷, D = Day, SI = signal intensities, WM = white matter, FB = fetal bradycardia (< 80 beats/min), MF = multiorgan failure, MA = meconium aspiration, MSA = meconium stained amniotic fluid, CP = cerebral palsy, SAH = subarachnoidal haemorrhage, NA = not available, ^* = lesion of antepartum origin.