Table 1

VZV findings and influenza A IgG antibodies for study infants (1-4) and reference (5-10) groups in three consecutive serum (S) and CSF samples, as well as antibody titres maternal sera during pregnancy (sample 1) and after delivery (sample 2)

PatientsSamplesInfant samples
Age of infantsVZV IgG (EIU) of infantsVZV IgG (EIU) serum:CSF ratioVZV IgG antibody indexVZV IgM of infantsInfluenza A IgG (EIU) of infants
SCSFSCSFS
1I4 d82108.2Not doneNot doneNegative116
II11 d5987.420.8NegativeNegative75
III7 m38Unspecified< 20
2I25 d65154.313.4NegativeNot done91
II62 d6688.3Not doneNegativeNegative51
III6 m< 20Positive< 20
3I9 d86117.89.3NegativeNegative103
II57 d76< 5Not doneNot doneNegativeNegative80
III11 m24Negative < 20
4I5 d58163.6Not donePositiveNot done36
II25 d111618.58.3PositiveUnspecified28
MeanI10.8 d72.813611.4
II38.8 d785.811.414
Mean differenceI-II28.0 d−5.37.3−5.4−3.0
5I1 d88< 5NegativeNegative35
II17 d51Not doneNegativeNot done37
6I11 d81< 5NegativeNegative58
II49 d87Not doneNegativeNot done22
7I5 d64< 5NegativeNegative100
II21 d64< 5NegativeNot done73
8I6 d75< 5NegativeNegative75
II21 d51< 5NegativeNot done46
III7 m< 20< 20
9I2 d63< 5NegativeNegative162
II51 d31< 5NegativeNegative120
III8 m< 20Not done76
10I3 d81< 5NegativeNegative95
II57 d46< 5Not doneNegative70
III6 m< 20Negative< 20
MeanI4.7 d75.3
II36 d55.0
Mean differenceI-II31.3 d20.3
Maternal samples
Gestational weeks/age of infantsVZV iGG (EIU) of mothersVZV IgM of mothersInfluenza A IgG (EIU) of mothers
SSS
6 h691-150 UnspecifiedNot done
16 h74Negative84
62 days141Positive123
8 h54Negative89
57 days86Negative107
14 h107Not doneNot done
25 days104Not doneNot done
11 h7687
48 days110 115
−32−28
15 h45Negative60
7 h22Positive68
12 h72Negative97
5 days73Unspecified95
15 h58Negative54
5 days64Negative67
10 h35Negative68
2 days41Negative147
14 h59Negative193
3 days62Negative86
12 h48.590
3, 8 days6099
−11.5−9
  • 1-150 At the gestational age of 16 weeks VZV IgG 102 EIU. At the age of 5 months VZV IgM weakly positive. The difference between the groups is significant (p=0.03).

  • EIU indicates antibody titre and it is obtained when the optical density (OD) of the sample in dilution 1:200 is compared with the OD of the positive control and multiplied by 100. Values ⩾ 100 are considered high and values ⩽20 negative in serum, and <5 negative in CSF.