Body weight before and after BAL, PaO2 , PaCO2 of animals (mean (SEM))
| Parameters | Group A (Exosurf) | Group B (Survanta) | |||||
|---|---|---|---|---|---|---|---|
| A1 (jet) | A2 (ultrasonic) | B1 (jet) | B2 (ultrasonic) | ||||
| Body weight (g) | 2894 (63) | 2933 (59) | 2957 (51) | 3020 (78) | |||
| PaO2 (mm Hg): | |||||||
| Before BAL | 297.5 (44.2) | 309.3 (35.7) | 319.4 (33.8) | 323.5 (15.2) | |||
| After BAL | 39.0 (4.8) | 36.2 (2.4) | 49.8 (2.1) | 50.1 (9.1) | |||
| p (paired t test) | 0.0048 | 0.0006 | 0.0055 | 0.0008 | |||
| After nebulisation (mins): | |||||||
| 0 | 37.4 (2.1) | 39.2 (1.8) | 37.0 (3.2) | 52.3 (8.6) | |||
| 30 | 43.4 (5.0) | 49.5 (6.0) | 40.3 (3.6) | 62.1 (17.1) | |||
| 60 | 50.9 (7.2) | 71.7 (5.7) | 55.1 (15.5) | 45.3 (9.1) | |||
| p (ANOVA) | 0.148 | 0.001 | 0.452 | 0.239 | |||
| PaCO2 (mm Hg): | |||||||
| Before BAL | 39.0 (4.4) | 34.6 (3.2) | 34.2 (6.3) | 37.9 (3.0) | |||
| After BAL | 59.1 (4.2) | 53.8 (5.6) | 60.0 (1.5) | 55.1 (6.7) | |||
| p (paired t test) | 0.027 | 0.014 | 0.0081 | 0.042 | |||
| After nebulisation (mins): | |||||||
| 0 | 56.6 (2.5) | 61.0 (4.0) | 67.1 (7.4) | 51.3 (10.0) | |||
| 30 | 58.8 (7.1) | 55.8 (3.4) | 68.9 (8.3) | 51.2 (8.8) | |||
| 60 | 56.8 (5.2) | 50.1 (1.8) | 62.6 (15.2) | 57.7 (9.5) | |||
| p (ANOVA) | 0.845 | 0.0066 | 0.926 | 0.108 | |||