Table 1

Results of biochemical investigations with encephalopathy (days 10 to 14)

ValueReference range
Plasma:
 Glucose (mmol/l)6.0-7.0> 2.5
 Bicarbonate (mmol/l)22-2520-24
 Calcium (mmol/l)2.36-2.662.20-2.65
 Magnesium (mmol/l)1.000.70-1.00
 AST (IU/l)23.5-42
 ALT (IU/l)85-42
 Uric acid (mmol/l)0.220.14-0.34
 Ammonia (μmol/l) (day 14)136< 40, < 150  sick newborn
 Amino acidsNormal profile
  Methionine (μmol/l)35< 96
  Tyrosine (μmol/l)50< 196
CSF:
 Lactate (mmol/l)1.86< 2.00
Urine:
 Amino acidsPungent smell,  normal profile
  Methionine (μmol/mmol creatinine)257-27
 Organic acids
  Day 11No odour,  normal profile
  Day 14Pungent smell,  normal profile