Patient characteristics before treatment1-150
| Characteristic | Indomethacin (n=20) | Ibuprofen (n=20) |
|---|---|---|
| Birthweight (g) | 1210 (360) | 1270 (450) |
| Gestational age (weeks) | 28.7 (1.9) | 29.0 (2.4) |
| Maternal medication: | ||
| Corticosteroids | 9 (45) | 10 (50) |
| Indomethacin | 7 (35) | 8 (40) |
| Ventilatory support (hours): | ||
| Mean MAP1-151 (cm H2O) | ||
| 24 | 9.1 (2.9) | 9.0 (2.9) |
| 48 | 9.0 (3.8) | 8.6 (2.7) |
| 72 | 7.8 (2.9) | 8.3 (2.8) |
| Mean FIO2(%) | ||
| 24 | 50 (17) | 44 (13) |
| 48 | 41 (17) | 43 (14) |
| 72 | 34 (12) | 40 (17) |
| Surfactant treated | 19 (95) | 15 (75) |
| Intraventricular haemorrhage: | ||
| Mild | 1 | 2 |
| Moderate | 1 | 1 |
| Severe | 2 | 0 |
| PDA evaluation: | ||
| Shunt: | ||
| Moderate | 11 | 12 |
| Large | 9 | 8 |
| Ductal diameter (mm) | 2.5 (0.7) | 2.6 (0.7) |
| LA:Ao ratio1-154 | 1.57 (0.20) | 1.57 (0.21) |
| Age at treatment (days) | 3.1 (0.5) | 3.2 (0.4) |