TY - JOUR T1 - Clinical aspects of incorporating cord clamping into stabilisation of preterm infants JF - Archives of Disease in Childhood - Fetal and Neonatal Edition JO - Arch Dis Child Fetal Neonatal Ed DO - 10.1136/archdischild-2018-314947 SP - fetalneonatal-2018-314947 AU - Ronny Knol AU - Emma Brouwer AU - Alex S N Vernooij AU - Frans J C M Klumper AU - Philip DeKoninck AU - Stuart B Hooper AU - Arjan B te Pas Y1 - 2018/04/21 UR - http://fn.bmj.com/content/early/2018/04/21/archdischild-2018-314947.abstract N2 - Fetal to neonatal transition is characterised by major pulmonary and haemodynamic changes occurring in a short period of time. In the international neonatal resuscitation guidelines, comprehensive recommendations are available on supporting pulmonary transition and delaying clamping of the cord in preterm infants. Recent experimental studies demonstrated that the pulmonary and haemodynamic transition are intimately linked, could influence each other and that the timing of umbilical cord clamping should be incorporated into the respiratory stabilisation. We reviewed the current knowledge on how to incorporate cord clamping into stabilisation of preterm infants and the physiological-based cord clamping (PBCC) approach, with the infant’s transitional status as key determinant of timing of cord clamping. This approach could result in optimal timing of cord clamping and has the potential to reduce major morbidities and mortality in preterm infants. ER -