@article {De Luca, author = {Daniele De Luca and Enrico Zecca and Mirta Corsello and Eloisa Tiberi and Carla Semeraro and Costantino Romagnoli}, title = {Attempt to improve transcutaneous bilirubinometry: a double blinded study Medick BiliMed versus Respironics BiliCheck}, year = {2007}, doi = {10.1136/adc.2007.121053}, publisher = {BMJ Publishing Group}, abstract = {Objectives: To compare the accuracy of a new transcutaneous bilirubinometer (BiliMed{\textregistered} Medick SA, Paris, France) with BiliCheckTM (Respironics, Marietta, GA- USA), a widely available instrument, and with total serum bilirubin measurement. Design: We conducted a prospective double blinded study comparing two devices. 686 healthy newborns needing their bilirubin measured were enrolled over a 4 month-period. Serum and transcutaneous bilirubin measurements were taken with both devices within 15 minutes. The order of use of the instruments was randomized. Setting: Well-baby nursery ward in a University Hospital, tertiary referral centre. Results: The linear regression analysis showed a better correlation between BiliCheckTM and serum bilirubin (r = 0.75) than between BiliMed{\textregistered} and serum bilirubin (r = 0.45). BiliCheckTM variability ({\textpm} 2 S.D. of the mean bias from serum bilirubin) was within -5.1/+3.7 mg/dl, while BiliMed{\textregistered} variability was within -5.7/+7.1 mg/dl. The ROC analysis (for serum bilirubin levels \> 12 mg/dl or \> 14 mg/dl) showed significantly higher areas under the curve for BiliCheckTM than those for BiliMed{\textregistered} ( p \< 0.0001). Conclusions: Despite the potential practical advantages of BiliMed{\textregistered} , the reduced diagnostic accuracy in comparison to BiliCheckTM does not justify its use in clinical practice.}, issn = {1359-2998}, URL = {https://fn.bmj.com/content/early/2007/11/15/adc.2007.121053}, eprint = {https://fn.bmj.com/content/early/2007/11/15/adc.2007.121053.full.pdf}, journal = {Archives of Disease in Childhood - Fetal and Neonatal Edition} }