Neonatal sepsis: Staphylococcus aureus as the predominant pathogen

Indian J Pediatr. 2001 Aug;68(8):715-7. doi: 10.1007/BF02752407.

Abstract

96 consecutive inborn neonates with blood culture proven bacterial sepsis during the period January to June 1997 were studied. Lethargy with refusal of feeds (28%), fever (28%) and respiratory distress (31.3%) were the major presenting features. Half of them (n = 48) were of early onset (< 48 hours) and the remaining half were of late onset (> 48 hours). Staphylococcus aureus (n = 59, 61.5%) was the predominant pathogen and 66% of them were methicillin resistant followed by Klebsiella pneumoniae (n = 24, 21.9), Escherichia coli (n = 13, 13.5%) and streptococci (n = 3, 3.1%). Antibiotic resistance was common, with the sensitivity to various antibiotics being ampicillin 19%, gentamicin 21.6%, cefotaxime 32.8%, amikacin 50%, chloromycetin 59.6% and ciprofloxacin 90.3%.

MeSH terms

  • Bacteremia / epidemiology
  • Bacteremia / microbiology*
  • Bacteremia / mortality
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • Cross Infection / mortality
  • Humans
  • India / epidemiology
  • Infant, Newborn
  • Staphylococcal Infections / complications
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus