Skip to content
Licensed Unlicensed Requires Authentication Published by De Gruyter April 26, 2011

Listeriosis in human pregnancy: a systematic review

  • Ronald F. Lamont EMAIL logo , Jack Sobel , Shali Mazaki-Tovi , Juan Pedro Kusanovic , Edi Vaisbuch , Sun Kwon Kim , Niels Uldbjerg and Roberto Romero

Abstract

Listeria is commonly found in processed and prepared foods and listeriosis is associated with high morbidity and mortality. Preventative measures are well prescribed and monitoring and voluntary recall of contaminated products has resulted in a 44% reduction in the prevalence of perinatal listeriosis in the USA. Pregnant women are at high risk for listeriosis, but symptoms are non-specific and diagnosis is difficult. The intracellular life-cycle of Listeria protects the bacterium from host innate and adaptive immune responses. Antibiotic treatment requires agents able to penetrate, distribute, and remain stable within host cells. Prolonged use of high-dose ampicillin can significantly improve neonatal outcome.


Corresponding authors: Ronald F. Lamont, BSc, MB, ChB, MD, FRCOG and Roberto Romero, MD Perinatology Research Branch, NICHD, NIH, DHHS Wayne State University/Hutzel Women’s Hospital 3990 John R, Box 4 Detroit, MI 48201, USA Tel.: +1 (313) 993-2700 Fax: +1 (313) 993-2694

Received: 2010-11-11
Revised: 2011-2-9
Accepted: 2011-2-11
Published Online: 2011-04-26
Published in Print: 2011-05-01

©2011 by Walter de Gruyter Berlin New York

Downloaded on 28.3.2024 from https://www.degruyter.com/document/doi/10.1515/jpm.2011.035/html
Scroll to top button