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Periodic Breathing and Oxygen Saturation in Preterm Infants at Discharge

Journal of Perinatology volume 22, pages 442–444 (2002)Cite this article

Abstract

OBJECTIVE: Periodic breathing (PB) is a common respiratory pattern in preterm infants. Our aim was to determine the influence of PB on the pattern of oxygenation in preterm infants with significant PB at discharge from hospital.

STUDY DESIGN: Overnight 12-hour recordings of arterial O2 saturation (SpO2), impedance breathing movement, nasal thermistor signals for airflow, and heart rate were performed in all preterm infants ≤34 weeks' gestational age at birth, prior to hospital discharge. Infants had recovered from their neonatal complications and were not receiving methylxanthines or supplemental oxygen. Data from 28 infants who had significant PB (≥5% of quiet time artifact free) were further analyzed. Gestational age at birth was (median, range) 32 (27–34) weeks, and gestational age at recording was 35 (33–37) weeks.

RESULTS: The baseline SpO2 was 98% (92–100%). During PB, all infants had episodes when SpO2 fell ≥5%, and all except one had episodes when SpO2 was <90%. Sixty episodes of prolonged desaturation (SpO2≤80% for ≥4 seconds) were recorded in 10 infants: 31 occurred during PB, 16 during hypopnea, 10 during apnea, and 3 occurred in the absence of these breathing patterns. During PB, nine infants (32%) had 1 to 13 episodes of prolonged desaturation, lasting 9 (4–76) seconds.

CONCLUSION: We conclude that PB is a common cause of prolonged desaturation in preterm infants at discharge.

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Authors and Affiliations

  1. Division of Neonatology, Department of Pediatrics, The Children's Regional Hospital at Cooper Hospital and University Medical Center, Camden, NJ, USA

    Nosrat M Razi MD, Michelle DeLauter MSN & Paresh B Pandit MD

  2. University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Camden, NJ, USA

    Nosrat M Razi MD, Michelle DeLauter MSN & Paresh B Pandit MD

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  1. Nosrat M Razi MD
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  2. Michelle DeLauter MSN
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  3. Paresh B Pandit MD
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Razi, N., DeLauter, M. & Pandit, P. Periodic Breathing and Oxygen Saturation in Preterm Infants at Discharge. J Perinatol 22, 442–444 (2002). https://doi.org/10.1038/sj.jp.7210762

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