Pulsed Doppler echocardiographic determination of time of ductal closure in normal newborn infants†
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2022, Microchemical JournalCardiopulmonary Adaptation During First Day of Life in Human Neonates
2018, Journal of PediatricsCitation Excerpt :The later rise in RVO after 10 hours of age, coinciding with the timing of ductal closure and decrease in PVR, provides biological plausibility. Our study confirms that DA is either closed or demonstrates restrictive left-to-right flow in most cases within 24 hours of birth.32-35 Although the dominant flow pattern is bidirectional, as seen in previous reports,27,36 we demonstrated that the percentage of right-left flow was ≤40% of total shunt duration in all cases by 30 minutes, suggesting pulmonary pressures to be subsystemic.12
Prophylactic and early targeted treatment of patent ductus arteriosus
2018, Seminars in Fetal and Neonatal MedicineCitation Excerpt :Lack of these within the first few hours of life is associated with ductal patency [10]. The sequence of closure usually starts at the pulmonary end with functional closure usually complete by 72 h of age in healthy term infants [11,12] but this may take longer in the preterm infant [13–15]. In normal newborn infants >36 weeks gestation, functional PDA closure has occurred in 42% by 24 h after birth, 78% by 40 h, 90% by 48 h and in all by 96 h [12].
Closure time of ductus arteriosus after birth based on survival analysis
2018, Early Human DevelopmentCardiovascular compromise in the preterm infant during the first postnatal day
2018, Hemodynamics and Cardiology: Neonatology Questions and Controversies
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Supported in part by National Institutes of Health Grants RR-05432 and HL-07293.
Presented at the 48th Annual Meeting of American Academy of Pediatrics, Section on Cardiology, October 13–18, 1979, San Francisco, California.
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Dr. Gentile's participation was supported by Italo-American Medical Education Foundation.