eLetters

628 e-Letters

  • CRP in the wrong context
    Nitin Rajput

    Unfortunately the authors have failed to understand the utility of CRP at 18-24 hours. This has a high negative predictie value but low positive predictive value. This means that while a low CRP is reassuring but a high value has to be evaluated in the clinical context. A high CRP should not be equal to a lumbar puncture. I should point that NICE guidelines do not recommend using CRP in isolation and clinical acumen sho...

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  • Re: Congenital Chylothorax in the UK: Findings from a BPSU epidemiological study
    Anja Bialkowski

    We are grateful to our colleagues Haines and Davis from the UK for their comments confirming many of our findings in their British population -based cohort. We agree that differences in findings (e.g., different rates of syndromal anomalies associated with congenital chylothorax) may simply be due to small numbers. It is nice to see that this rare but serious condition is receiving more scientific attention

    Confl...

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  • Missed opportunties for qualitative insight
    Morris Gordon

    I read this Randomised controlled trial with great interest. I applaud the authors for including focus group discussions in the study.

    A study that simply tells us 'whether' parental presence on a bedside round is appropriate is of limited value and so deeper qualitative discourse is needed. This can consider more meaningful questions such as 'how', 'why' and 'when' such parental presence impacts the neonatal j...

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  • Re:Response to Letter Management of infantile haemangiomas of the eyelid
    Deborah K. VanderVeen

    We appreciate the feedback and clarity provided by the letter in response to our review article. We agree in principle with the authors that beta-blockers have rapidly become the standard of care for infantile haemangiomas (IHs), and for this reason listed it first in our short review of treatment options. Indeed, a recent meta-analysis of 35 studies (representing 572 paediatric patients with IHs) strongly supported the...

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  • In response to: Early onset neonatal sepsis: diagnostic dilemmas and practical management.
    Job LB Gieling

    We read with interest the review by AR Bedford Russell and F Kumar[1] about challenges in diagnosing EONS. The authors state to await a 100% sensitive and 100% specific test. In theory, this gold standard is obtained by observing infants while withholding antibiotics, which obviously is unacceptable. Instead combinations of laboratory and clinical signs are used to exclude EONS. Understandably, these tests must have hi...

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  • Numbers from flow-chart, text and tables do not match
    GAURI A. OKA

    Dear Sir, First let me congratulate you for the phenomenal work that you have done at Safdarjung Hospital.

    On reading your paper, I found discrepancies in numbers in the flow chart (Fig 1) and Table 2: viz. out of 1599 abnormal babies on pulse oximetry, Echo confirmed 18 major and 15 critical CHDs. However, further in the text and in table 2, the corresponding numbers are cited as 39 major and 22 critical CHDs...

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  • Measurements from preterm infants to guide face mask size
    Veronica Mardegan

    We read with interest the article by O'Shea et al., recently published in the Archives of Disease in Childhood Fetal and Neonatal Edition.1 Faces of preterm infants were photographed and analyzed by using a software; they then were compared with the size of the most commonly available face masks (Laerdal 0/0 and Fisher & Paykel Infant Resuscitation Masks "small" and "extra small"). Authors concluded that the smallest...

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  • Re: Effectivity of ventilation by measuring expired CO2 and RIP during stabilisation of preterm infants at birth.[1]
    Anne Greenough

    We were pleased that our findings [2] and those of Tunell's group [3] have been confirmed in the recent paper by van Vonderen et al [1], that is the inspiratory efforts of prematurely born infants coinciding with inflations during resuscitation at birth are critical in increasing the expired carbon dioxide levels. In addition, we have previously published the relationship between expired tidal volume and expired carbon dio...

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  • Povidone-iodine pleurodesis for congenital chylothorax of the newborn (Resch et al.)
    Roland Hentschel

    To the editor: We read with interest the case report on the use of polividon-iodine (PVI) to perform chemical pleurodesis in newborns and the short literature review on further 12 cases in 5 publications by Resch et al.[1]. We found another most recent publication from 2015 on a series of 5 young infants with a success rate of 80%[2]. We agree with Resch et al., who conclude that "the risk-benefit assessment of PVI pleur...

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  • Herpes virus must be considered as one of the causes for late onset sepsis
    Dushyant Batra

    Dear Editor, Archives of Disease of childhood: Foetal and Neonatal edition

    We read the review article by Dong et al(1) with interest. We wanted to congratulate the authors on a very balanced and clinically relevant review; highlighting the epidemiological, therapeutic and preventative aspects of late onset sepsis caused by bacteria and fungi. We believe that the review would have been even more clinically releva...

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