100 e-Letters

published between 2009 and 2012

  • Delay in identification of oesophageal atresia in a preterm neonate with radial club hand due to coiling of 5F nasogastric tube
    Gengaimuthu Karthikeyan

    We had a 29 weeks/1.29kg/male neonate born with left radial club hand deformity. The resident attending the resuscitation had 'passed' a 5F nasogastric tube and certified the orifices patent. Baby was admitted in NICU, had no respiratory distress and was started on trophic feeds of 2ml 2 hourly by 5F nasogastric tube passed via the nostril which the baby 'accepted'. After 12 hours baby developed worsening respiratory dist...

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  • Etiology of perinatal stroke; a role for prothrombotic coagulation factors?
    Spalice Alberto

    We read with grat interest the article on perinatal stroke of J Harteman and co-workers. In our experience in perinatal stroke, multiple, often coexisting, risk factors are involved, varying from maternal and fetal risk factors during pregnancy and delivery, to infectious causes and cardiac diseases as well as medical interventions and congenital prothrombotic coagulation factors. We have performed a retrospective study t...

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  • ROP in larger babies gives insight into basic mechanisms but poses a clinical challenge
    Alistair R Fielder

    Aggressive posterior retinopathy of prematurity (APROP), the most aggressive form of ROP which carries a poor prognosis despite treatment, is seen only rarely in the UK. It was formally described in 2005 1 and is thought to be confined to the most immature preterm baby when the developing retinal vessels have reached only zone I or posterior zone II. This belief was challenged most effectively by Shah et al who recently...

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  • Measuring the wrong force leads to unjustified conclusions
    Andrew J McArdle
    Dear Editor,

    While commending van Vonderen et al. for an interesting and well-executed study on forces applied during mask ventilation of neonates1, I have two criticisms.

    Firstly, the study was inappropriate to discover whether in compensating for mask leak, clinicians "[press] down on the mask too hard, leading to obstruction of the nose and mouth.1" In measuring the force transmitted...
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  • Do not forget cystic fibrosis
    Samuele Naviglio

    I read with interest the article by Best et al. regarding the epidemiology of small intestinal atresia. In the evaluation on the associated conditions nevertheless the Authors do not include nor mention the association of intestinal atresia with cystic fibrosis. In fact this is an association which should never be forgotten while caring for an infant with small intestinal atresia. Up to 13% of children with jejunoileal...

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  • "SHC" versus "WBC" in therapeutic hypothermia for HIE
    Biju M John

    Dear Editor, We read with interest the article by Sarkar et al(1) on distribution and severity of hypoxic-ischaemic lesions on brain MRI following therapeutic cooling .It is perhaps one of the very few studies which has attempted to look at the possible differences between the two forms of cooling for hypoxic ischemic encephalopathy(HIE).Brain MRI is increasingly being utilized as a good biomarker of long term neurologi...

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  • Re:Response to: Drugs used for comfort care after withdrawal of intensive treatment in tertiary neonatal units in the UK1.
    Rajiv Chaudhary

    Dear sir I am grateful for Dr. Power's comments and the opportunity to respond to them. We do know that withdrawal of intensive treatment can pose many challenges. Once decision is agreed to withdraw intensive treatment a significant time elapses before ventilatory support is withdrawn. This duration is very much dependent on individual cases and is guided by clinical, social, religious and familial factors. Respirator...

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  • Minimally, moderately, or ... equally invasive surfactant therapy?
    Paolo Biban

    Dear Editor, I read with interest the article by Dargaville et al (1), about the feasibility and potential effectiveness of MIST, i.e. minimally-invasive surfactant therapy, in preterm infants with respiratory distress syndrome. Similarly to other recent techniques (2,3), the ultimate goal of MIST is that of delivering surfactant while avoiding both "standard" tracheal intubation and mechanical ventilation. The authors ha...

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  • Subcutaneous air
    Kenneth L Harkavy

    The authors present an infant whose free air spread from the thorax to the neck and scalp. Many years ago we reported a term infant with subcutaneous air. At a community hospital the infant developed a pneumothorax and possible pneumomediastinum. Over the course of four hours, he progressed to bilateral tension pneumothoraces. The transport team performed bilateral thoracenteses at 5 hours of age. Chest drains were plac...

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  • The new model of continuous glucose monitoring sensor "ENLITE" in preterm infants.
    Enrico Zecca

    Dear Editor, We read with interest the paper by K Beardsall et al about the validation of the continuous glucose monitoring sensor (CGMS) in preterm infants (1). In this study the author confirms in a large population the good results of her previous pilot study (2). Apparently, the recent study utilized the first model of Medtronic CGMS, whose sensor was linked to the monitor and did not have real time read outs. Howe...

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