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Clinical interventions to reduce the development of retinopathy of prematurity (ROP) have been limited because postnatal risk factors associated with ROP are difficult to alter in clinical practice. Specifically, the ability to restrict oxygen administration to prevent ROP must be balanced with the need to provide sufficient supplemental oxygen to prevent death. Accordingly, the most recent Cochrane review1 shows that compared with a higher oxygen saturation target range, a lower target range significantly decreased the incidence of surgical ROP (relative risk 0.72) at the same that …
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