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MenB (Bexsero) immunisation side effects in extremely premature infants (<28 weeks)
  1. Arindam Mukherjee1,
  2. Devdeep Mukherjee2,
  3. Azita Rajai3,
  4. Srividhya Senthil4,
  5. Ngozi Edi-osagie5
  1. 1 Department of Neonatology, St Marys Hospital, Central Manchester University Hospitals NHS Foundation Trust, University of Manchester, Manchester, UK
  2. 2 Department of Neonatology, St Marys Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
  3. 3 Department of Research and Innovation, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK
  4. 4 Department of Neonatology, St Marys Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK
  5. 5 Department of Neonatology, St Marys Hospital, Central Manchester University Hospitals NHS Foundation Trust, University of Manchester, Manchester, UK
  1. Correspondence to Dr Arindam Mukherjee, Consultant Neonatologist and Honorary Senior Lecturer, Department of Neonatology, St Marys Hospital, Central Manchester University Hospitals NHS Foundation Trust; arindam.mukherjee{at}cmft.nhs.uk

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On 1 September 2015, the UK became the world’s first country to introduce a novel meningococcal B vaccine (Bexsero) into its national childhood immunisation programme. Bexsero is the only market authorised meningococcal B vaccine in the UK. Meningococcal B strains accounts for ~80% of all laboratory confirmed cases of invasive meningococcal disease (IMD) in England and Wales1. Bexsero is estimated to protect against 73%–88% of the meningococcal B strains causing invasive disease in England and Wales2

After observing more instances of clinical instability in our immunised neonates following the introduction of the new …

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