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Oral sucrose for acute pain studied in more than 7000 neonates, but many questions remain
  1. Monique van Dijk1,2,
  2. Dick Tibboel2,
  3. Sinno Simons1
  1. 1Division of Neonatology, Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands
  2. 2Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands
  1. Correspondence to Monique van Dijk, Department of Pediatric Surgery and Pediatrics, Erasmus MC-Sophia Children's Hospital, Wytemaweg 80, Rotterdam 3015 CN, The Netherlands; m.vandijk.3{at}erasmusmc.nl

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Oral sucrose for infants is not new at all; it is comparable with the ‘sugar tit’ (a pacifier made from cloth wrapped around sugar) that was used as early as the 18th century.

In many neonatal intensive care units neonates are given a few drops of orally administered sucrose (with or without a pacifier) before skin-breaking procedures to relieve pain. Its effectiveness after heel lance, venepuncture and intramuscular injection was confirmed in …

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